《The role of  Methyl-CpG Binding Protein 2 in Rett Syndrome》专家PPT内容预览
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《The role of  Methyl-CpG Binding Protein 2 in Rett Syndrome》专家PPT内容简介
    Rett Syndrome is a neurodevelopmental disorder
    Hypotonia – loss of muscle tone 
    Apraxia —inability to perform motor functions 
    loss of use hands
    repetitive hand movements
    diminished eye contact
    gait abnormalities
    lack of speech development
    Other Symptoms
    autism like behaviors
    toe walking
    sleep problems
    cognitive disabilities
    seizures
    breathing problems
    teeth grinding
    difficulty chewing

    MECP2 GO Terms Suggest Function
    Biological Process
    Negative regulation of transc**tion from RNA polymerase II promoter
    Cellular Component
    Mitochondrion
    Nucleolus
    Nucleus *Also noted in Uniprot 
    Molecular Function
    DNA binding 
    Double stranded methylated DNA binding
    Protein binding 
    Transc**tion corepressor activity


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