《Management of Babies Born to HBsAg- Positive Mothers》专家PPT内容预览
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《Management of Babies Born to HBsAg- Positive Mothers》专家PPT内容简介
    About Hepatitis B Infection
    Spread by:
    Sexual
    Parenteral
    Perinatal 
    Acute and/or Chronic 
    Chronic infection is a leading cause of liver disease.

    Hepatitis B – Clinical Features
    Acute
    New infection
    Symptoms more common among adults
    Children often asymptomatic.
    Two possible outcomes:
    Infection resolves: person develops immunity
    infection does not resolve and the person continues to carry the virus  
    Chronic
    Individual carries the virus for >6 months and does not develop anti-bodies to the surface antigen (anti-HBsAg)
    Silent infection
    People that become infected as children are more likely to become chronically infected.

    HBV Testing
    HBsAg:
    (hepatitis B surface antigen)
    Marker of current infection
    Neutralization
    HBsAb:
    (hepatitis B surface antibody)
    Marker of immunity
    HBeAg: 
    (hepatitis B e antigen)
    Marker of high infectivity
    Anti-HBe 
    (hepatitis B e antibody)
    Marker of low infectivity
    Anti-HBc IgM 
    (hepatitis B core antibody IgM)
    If +, acute infection
    if negative and HBsAg +, chronic infection
    Anti-HBc 
    (hepatitis B core antibody)
    Marker of current or previous infection

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