《白癜风诊断和治疗指南》内容预览

This detailed and user-friendly guideline for the diagnosis and management ofvitiligo in children and adults aims to give high quality clinical advice, based onthe best available evidence and expert consensus, taking into account patientchoice and clinical expertise.
The guideline was devised by a structured process and is intended for use bydermatologists and as a resource for interested parties including patients. Recom-mendations and levels of evidence have been graded according to the methoddeveloped by the Scottish Inter-Collegiate Guidelines Network. Where evidencewas lacking, research recommendations were made.
The types of vitiligo, process of diagnosis in primary and secondary care, andinvestigation of vitiligo were assessed. Treatments considered include offering notreatment other than camouflage cosmetics and sunscreens, the use of topicalpotent or highly potent corticosteroids, of vitamin D analogues, and of topicalcalcineurin inhibitors, and depigmentation with p-(benzyloxy)phenol. The use ofsystemic treatment, e.g. corticosteroids, ciclosporin and other immunosuppressiveagents was analyzed.
Phototherapy was considered, including narrowband ultraviolet B (UVB), psora-len with ultraviolet A (UVA), and khellin with UVA or UVB, along with combi-nations of topical preparations and various forms of UV. Surgical treatments thatwere assessed include full-thickness and split skin grafting, mini (punch) grafts,autologous epidermal cell suspensions, and autologous skin equivalents. Theeffectiveness of cognitive therapy and psychological treatments was considered.Therapeutic algorithms using grades of recommendation and levels of evidencehave been produced for children and for adults with vitiligo.

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