关键信息

    治疗上皮性卵巢癌（EOC）的历史标准是卡铂+紫杉醇。依据非随机研究，剂量密集化疗可能提高晚期疾病的应答率，而耐受性可以保持。

    该综述的作者评估了使用紫杉醇强化治疗晚期EOC的基本原理和III期试验结果。

    TAKE-HOME MESSAGE

    The historical standard of care for advanced epithelial ovarian cancers （EOC） is carboplatin and paclitaxel. Based on nonrandomized studies, dose-dense chemotherapy may improve response rates in advanced disease, and tolerability may be maintained.

    The authors of this review evaluate the rationale and phase III trial results associated with dose-dense delivery of paclitaxel in advanced EOC.