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    在这项纵向队列研究中，研究者对421对母女进行评估。研究发现，与血糖水平位于下五分位数母亲生出的女儿相比，妊娠糖尿病母亲生出的女儿BMI≥85th、体重身高比或体脂百分比位于上四分位数风险显著增加（OR,2.80–3.56）。此外，该研究还发现，患有妊娠糖尿病，且孕前BMI水平较高的母亲生出的女儿肥胖症患病率最高。

    该研究提示，为了降低女性后代肥胖症发生风险，需要对妊娠糖尿病进行筛查和干预。

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    The authors of this longitudinal study evaluated 421 mother–daughter pairs. Compared with daughters born to mothers who had blood glucose levels in the lowest quintile, daughters born to mothers who had gestational diabetes mellitus had increased odds of having a BMI ≥85th percentile or of being in the highest quartile for weight–height ratio or percent body fat （OR, 2.80–3.56）。 The highest rates of adiposity in daughters were seen for mothers who had gestational diabetes and high pregravid BMI.

    Screening and intervention for gestational diabetes are warranted to decrease the risk for adiposity in female offspring.

    Diabetes Care

    Maternal Hyperglycemia During Pregnancy Predicts Adiposity of the Offspring

    Diabetes Care 2014 Nov 01;37（11）2996-3002, A Kubo, A Ferrara, GC Windham, LC Greenspan, J Deardorff, RA Hiatt, CP Quesenberry, C Laurent, AS Mirabedi, LH Kushi

    From MEDLINE?/PubMed?, a database of the U.S. National Library of Medicine.

    This abstract is available on the publisher's site.

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    Copyright ? 2014 Elsevier Inc. All rights reserved.