调胃冲剂治疗功能性消化不良765例临床疗效观察 内容预览:
观察以健脾疏肝法组成的调胃冲剂结合辨病论治,治疗功能性消化不良(FD)临床疗效,探讨其临床治疗规律。方法:采用大样本临床观察方法。结果:共治疗765例,显效568例(74.25%)、有效156例(20.39%)、无效41例(5.36%)、总有效率为94.64.。结论:通过大样本临床观察,本病基本病机变化是脾虚肝郁,胃气不和,以健脾化湿,疏肝和胃法为主结合辨病论治符合其病机演变规律。
Abstract:Objective:to observe the chinical curative effect of treating FD with stomach-adjusting preparation made by the method of invigorating the spleen and relkeving depression of the liver-qi as well as treatment with disease differentiation,and make research in its clinical treatment law.Method:clinical observation with major samples was adopted.Result:Among the 765 cases,568 cases had marked effect(74.25%),156cases had effect(20.39%),and 41 cases had no effect(5.36%).The whole effective rate reached 94.64%.Conclusion:according to the clinical observation of mjajor samples,the basic pathological change of FD is the insufficiency of the spleen and the stagnation of the liver-qi as the disorder of the stomach-qi,therefore,the method of invigorating the spleen and removing dampness,relieving the depression of the liver-qi and adjusting stomach,and treatment with disease differentation was the right choice.
Key words:functional dyspepsia;TCM treatment;method of invigorating the spleen & relieving the stagnation of the liver-qi;treatment with disease differentiation
根据对FD脾虚肝郁病机关键的认识,以健脾化湿,疏肝和胃为法组成调胃冲剂。从1997年1月~1999年12月应用调胃冲剂结合辨病论治治疗FD765例,取得了较好的临床疗效,现将结果报告如下。
西医诊断标准 主要临床症状:上腹饱胀,餐后加重,早饱,上腹痛痛,嗳气、恶心呕吐,烧心反酸,症状持续4周以上;内镜检查正常或排除溃疡、肿瘤等病变;实验室、B超及X线检查排除了肝胆、胰腺的器质性病变。病情诊断:根据症状的轻重程度分为3级。症状轻,经提示病人能意识到症状的存在为Ⅰ级;病人意识到症状存在,就诊时作为主诉叙述,但正常活动未受到限制为Ⅱ级;病人仅意识到症状存在,且正常活动受到限制为Ⅲ级。
中医辨证标准 脾虚肝郁:纳少,腹胀、痞满、食后尤甚,胃脘隐痛、时轻时重,便溏,肢体倦怠,面色少华,舌质淡,苔薄白,脉细无力。肝胃不和:脘胁胀满疼痛,嗳气,恶心呕吐,烧心反酸,舌质淡红舌或尖红,苔薄白,脉弦。脾胃阴虚:胃脘痞胀隐疼,饥不欲食,少食则饱,干呕,烧心,口燥咽干,或大便干结,或形体消瘦,舌质红少苔,脉细数。兼证诊断要点:兼湿热者症见口干苦、粘腻,小便短赤,大便粘腻不爽,舌红、苔黄厚腻,脉滑或滑数。兼血瘀者症见胃脘刺痛、入夜尤甚、疼痛拒按,舌质暗或有瘀点、瘀斑,脉细涩。
凡符合FD诊断标准者,根据患者意愿皆可作为本研究观察对象。伴有严重心、肾疾患、孕妇以及不能按规定用药而无法判断疗效者除外。一般资料 共观察765例,其中男362例,女403例;年龄:18~70岁,平均年龄32.6岁;病程:1个月~12年,平均2.3年;病情:Ⅰ级412例,Ⅱ级273例,Ⅲ级80例;中医辨证:脾虚肝郁472例,肝胃不和216例,脾胃阴虚77例;兼证:湿热106例,血瘀92例。
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