中国人胃癌的预后因素-石元凯 内容预览： 

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中国人胃癌的预后因素-石元凯 内容简介：

    ClinicalPrognosticFactorsinGastricCancerinChinesePatients:

    ExperiencefromtheCancerHospital/Institute,

    ChineseAcademyofMedicalSciences

    YuankaiShi,M.D.

    DepartmentofMedicalOncology,

    CancerHospital/Institute,

    ChineseAcademyofMedicalSciences（CAMS）

    Background

    Gastriccancerworldwidein2002:

    4thmostcommoncancer,2ndmostcommoncauseofdeath,

    2/3patientsindevelopingcountries,42%oftheminChina

    ParkinDM,etal.CACancerJClin.2005;55:74

    5-yearoverallsurvival:15%-54%

    ParkinDM,etal.CACancerJClin.2005;55:74

    GastriccancerinChinain2005

    Incidence:

    376,000newcases

    Thirdmostcommoncancer

    Mortality:

    24.71/105

    Thirdcauseofdeathfromcancer

    BehindLungcancerandLivercancer

    http://www.moh.gov.cn

    Objective

    Toevaluatethetherapeuticeffectsandprognosticfactorsinpatientswithoperablegastriccancer

    Toconstructaprognosticmodel

    aterialsandmethods

    Identifyprognosticfactorswithdatafrom1043ptstreatedwithcombinedmodalitytherapybasedongastrectomy,between1999and2002,intheCancerHospital,CAMS

    Constructprognosticmodelwithdatafrom1284ptswithcombinedmodalitytreatmentbasedongastrectomy,between1999-2006,intheCancerHospital,CAMS

    Statistical**ysis

    LifeTable,Coxhazardproportionalmodel,Logisticregressionmodel

    Results

    5-year

    39%

    15%

    1043ptswithoperablegastriccancer

    Mediansurvival:39.5mo

    medianrelapse-freesurvival:22.7mo

    5-yOS:39%

    5-yRFS:15%

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