Pediatric Solid Abdominal Tumors Culpepper

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Pediatric Abdominal Tumors: A Focus on Wilms’ Tumor
Chris Culpepper, MD
General Surgery Grand Rounds
5/25/11
Objectives
To discuss:
The most common pediatric solid abdominal tumors
Epidemiology, clinical presentation, and associated congenital syndromes involved in Wilms’ tumor
Surgical management
Staging and postoperative chemoradiation therapies in Wilms’ tumor


Solid Abdominal Tumor
2-year-old boy complains of abdominal pain and loss of appetite. Physical exam is significant for a large palpable abdominal mass.

Differential diagnosis:
Neuroblastoma
Rhabdomyosarcoma 
Hepatoblastoma
Nephroblastoma (Wilms’ tumor)
Solid Abdominal Tumors
Neuroblastoma
Most common malignant solid abdominal tumor in children
Derived from neural crest tissue
May arise anywhere along the sympathetic ganglia
Most common location is adrenal medulla
Average age at presentation is 1-2 years
70%
>1 y/o – overall survival

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