《2008BAD基底细胞癌的治疗指南》内容简介：

    There are several effective modalities available to treat basalcell carcinoma （BCC）。Guidelines aim to aid selection of themost appropriate treatment for individual patients. Carefulassessment of both the individual patient and certain tumour-specific factors are key to this process.

    《2008BAD基底细胞癌的治疗指南》内容预览：

    BCC is a slow-growing, locally invasive malignant epidermalskin tumour predominantly affecting caucasians. The tumourinfiltrates tissues in a three-dimensional fashion3through theirregular growth of subclinical finger-like outgrowths whichremain contiguous with the main tumour mass.4,5Metastasisis extremely rare6,7and morbidity results from local tissueinvasion and destruction particularly on the face, head andneck. Clinical appearances and morphology are diverse, andinclude nodular, cystic, superficial, morphoeic （sclerosing），keratotic and pigmented variants. Common histological sub-types include nodular （nBCC）， superficial （sBCC） and pig-mented forms in addition to morphoeic, micronodular,infiltrative and basosquamous variants which are particularlyassociated with aggressive tissue invasion and destruction.8Perivascular or perineural invasion are features associated withthe most aggressive tumours.

    Patient-specific factors which may influence the choice oftreatment include general fitness, coexisting serious medicalconditions, and the use of antiplatelet or anticoagulant medi-cation. A conservative approach to asymptomatic, low-risklesions will prevent treatment causing more problems than thelesion itself. Even when dealing with high-risk BCC aggressivemanagement may be inappropriate for certain patients, espe-cially the very elderly or those in poor general health, when apalliative rather than a curative treatment regimen may be inthe best interests of the patient.

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