《2011NICE 2型糖尿病预防指南》内容预览

The Department of Health (DH) asked the National Institute for Health andClinical Excellence (NICE) to produce public health guidance on theprevention of type 2 diabetes mellitus among high-risk groups.
The referral was divided into two separate pieces of guidance. The first (thisguidance) originally set out to address the prevention of ‘pre-diabetes’ amongadults aged 18–74 in communities at high risk of developing type 2 diabetes.The second set out to focus on preventing the progression from ‘pre-diabetes’to type 2 diabetes.
However, in January 2011 the World Health Organization (WHO)recommended that glycated haemoglobin (HbA1c) could be used as analternative to standard glucose measures to diagnose type 2 diabetes amongnon-pregnant adults. HbA1clevels of 6.5% (48 mmol/mol) or above indicatethat someone has type 2 diabetes – but there is no fixed point to indicatewhen someone has ‘pre-diabetes’. (Increasing levels of HbA1c,up to the 6.5%(48 mmol/mol) cut-off point, mean someone is at increasing risk of type 2diabetes.)
The title of this guidance has been changed since it went out for consultationto reflect this move away from recognising ‘pre-diabetes’ as a separatecondition. However, the overall range and scope of the content remains thesame. The second piece of guidance will consider the effectiveness and costeffectiveness of interventions to prevent type 2 diabetes among individuals athigh-risk.
Factors which influence someone’s risk of type 2 diabetes include: weight,waist circumference, age, physical activity and whether or not they have aprevious history of gestational diabetes or a family history of type 2 diabetes.In addition to these individual risk factors, people from certain communitiesand population groups are particularly at risk. This includes people of South

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