2010 AHA/ASA 美国卒中或短暂性脑缺血发作患者卒中二级预防指南   内容预览：

    The aim of this statement is to provide clinicians with the most up-to-date evidence-based recommendations for the prevention of ischemic stroke among survivors of ischemic stroke or TIA. A writing committee chair and vice chair were designated by the Stroke Council Manusc**t Oversight Committee. A writing committee roster was developed and approved by the Stroke Council with representatives from neurology, cardiology, radiology, surgery, nursing, pharmacy, and epidemiology/biostatistics. The writing group conducted a comprehensive review and synthesis of the relevant literature. The committee reviewed all compiled reports from computerized searches and conducted additional searches by hand. These searches are available on request. Searches were limited to English-language sources and human subjects. Literature citations were generally restricted to published manusc**ts appearing in journals listed in Index Medicus and reflected literature published as of August 1,2009. Because of the scope and importance of certain ongoing clinical trials and other emerging ***rmation, published abstracts were cited for ***rmational purposes when they were the only published ***rmation available, but recommendations were not based on abstracts alone. The references selected for this document are exclusively for peer-reviewed papers that are representative but not allinclusive, with priority given to references with higher levels of evidence. All members of the committee had frequent opportunities to review drafts of the document and reach a consensus with the final recommendations. Recommendations follow the American Heart Association (AHA) and the American College of Cardiology (ACC) methods of classifying the level of certainty of the treatment effect and the class of evidence

    本声明旨在为临床医生提供在缺血性卒中或TIA患者中预防缺血性卒中的最新循证推荐。写作委员会主席和副主席由卒中委员会著述监督委员会 (Stroke Council Manusc**t Oversight Committee)指定，其成员名单由卒中委员会拟定和批准，由来自神经病学、心脏病学、放射学、外科学、护理学、药剂学和流行病学／生物统计学等专业 的代表组成。写作组对相关文献进行了全面的回顾和综合。委员会回顾了通过计算机检索和进一步的手工检索获得的所有汇编报告。如有需要，可提供这些检索结 果。检索限于以人为对象的英文文献。文献引文通常限于医学索引(Index Medicus)列出的杂志于2009年8月1日之前发表的文献。鉴于某些正在进行的临床试验和其他新信息的重要性，如果摘要是唯一可获得的公开发表资 料，亦可出于情报目的予以引用，但不能单独在摘要基础上做出推荐。本文所选用的参考文献均为经过同行评议的具有代表性的论文，但并不包括全部文献，而是优 先选取具有更高证据水平草案，并就最终推荐达成共识。本指南的推荐意见遵循美国心脏协会和美国心血管病学学会关于疗效确切性水平和证据等级的分类方案。

    1.TIA和缺血性卒中亚型的定义

    2.所有TIA或缺血性卒中患者的危险因素控制

    3.大动脉粥样硬化患者的干预方法

    4.心源性栓塞的内科治疗

    5.非心源性栓塞性卒中或TIA(特别是动脉粥样硬化性、腔隙性或原因不明性梗死)的抗栓治疗

    6.其他特殊病因卒中患者的治疗

    7.女性卒中

    8.颅内出血后抗凝治疗的应用

    9 .实施指南的特殊方法以及指南在高危人群中的应用

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