Professionals, who are likely to be exposed to the live rabies virus through theirwork should receive pre-exposure vaccination. This include veterinarians,veterinary technicians working in rabies infected areas, particularly thosedirectly involved in mass vaccination campaigns of dogs and wildlife andlaboratory personnel handling suspect samples, animals and live rabies viruses.
Post-exposure prophylaxis may be discontinued if the animal involved is a dog or cat that remainshealthy for an observation period of 10 days after the exposure occurred; or if the animal is humanelykilled and proven to be negative for rabies by a reliable diagnostic laboratory using a prescribed test.
If the animal at the origin of exposure is suspected of being rabid and is not apprehended, PEP shouldbe instituted immediately.initiation of PEP should not await the results of veterinary laboratory diagnosis or be delayed by dogobservation when rabies is suspected,
In areas where canine or wildlife rabies is enzootic, adequate laboratory surveillance is in place, anddata from laboratory and field experience indicate that there is no infection in the species involved,local health authorities may not recommend anti-rabies prophylaxis.