《2009高度发育不良Barrett食管治疗指南》内容简介：

    The management of Barrett's esophagus with high-grade dysplasia is controversial. The standard of care hastraditionally been esophagectomy. However, a number oftreatment options aimed at esophageal preservation areincreasingly being utilized by many centers.

    《2009高度发育不良Barrett食管治疗指南》内容预览：

    Histological evaluation of high-grade dysplasiashould be undertaken by two pathologists expe-rienced in interpreting esophageal metaplasiaand dysplasia. （Level C Evidence）Class IIa

    It is reasonable to limit endoscopic surveillance ofhigh-grade dysplasia to high-volume centers withspecific expertise in the management of Barrett'sesophagus and preferably performed in the con-text of a clinical trial. （Level B Evidence）Class IIb

    Surveillance may be considered for patients withflat, unifocal high-grade-dysplasia as they are atlower risk for progression to cancer compared topatients with multifocal HGD or those with dyspla-sia-associated lesions or masses. （Level B Evidence）

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